4-Chloro-2-methylthiopyrimidine → 4-Methylbenzyl 4-({[2-(methylsulfanyl)-4-pyrimidinyl]amino}methyl)-1-piperidinecarboxylate

HRID 171668Notes

Reaction equation

HRID 171668 reaction equation
[Cl:1][c:2]1[n:3][c:4]([S:8][CH3:9])[n:5][cH:6][cH:7]1.[NH2:10][CH2:11][CH:12]1[CH2:13][CH2:14][N:15]([C:18](=[O:19])[O:20][CH2:21][c:22]2[cH:23][cH:24][c:25]([CH3:28])[cH:26][cH:27]2)[CH2:16][CH2:17]1>>[c:2]1([NH:10][CH2:11][CH:12]2[CH2:13][CH2:14][N:15]([C:18](=[O:19])[O:20][CH2:21][c:22]3[cH:23][cH:24][c:25]([CH3:28])[cH:26][cH:27]3)[CH2:16][CH2:17]2)[n:3][c:4]([S:8][CH3:9])[n:5][cH:6][cH:7]1

Participants

3

Reactant 2

HCID 971134-Chloro-2-methylthiopyrimidineHCID 161094174-Methylbenzyl 4-(aminomethyl)1-piperidinecarboxylate

Product 1

HCID 101347674-Methylbenzyl 4-({[2-(methylsulfanyl)-4-pyrimidinyl]amino}methyl)-1-piperidinecarboxylate

Sources & evidence

ORD record
ord-c83d72e451cf4f70b9926b8fd937b6ac
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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