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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1716714Generated: October 26, 2026

3-Pyridineacrylic acid ethyl ester → 3-(1H-Indol-6-yl)-3-pyridin-3-yl-acrylic acid ethyl ester

https://huagongshe.com/reaction/1716714

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Pyridineacrylic acid ethyl esterHCID 583337—
Reactant6-BromoindoleHCID 676493—
Product3-(1H-Indol-6-yl)-3-pyridin-3-yl-acrylic acid ethyl esterHCID 67355924—

Reaction Steps

3-(1H-Indol-6-yl)-3-pyridin-3-yl-acrylic acid ethyl ester CLVII was prepared from 6-bromo-1H-indole and 3-pyridin-3-yl-acrylic acid ethyl ester using the procedure described above for preparation of 3-(3-Cyano-1H-Indol-4-yl)-3-phenyl-acrylic acid ethyl esterLVIII (Example 14).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07803830B2
Source datasetuspto-grants-2010_09
ORD IDord-c2a717681ed147959a252557ff18cc94
Source noteuspto-grants-2010_09