Trifluoroacetic acid → HCID 59831768, compound

HRID 1716734Notes

Reaction equation

HRID 1716734 reaction equation
FC(F)(F)C([O-])=O.[CH3:8][O:9][C:10]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][C:17]=2[CH:19]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[CH2:20][C:21]([NH:23][CH3:24])=O)[NH:12][N:11]=1.FC(F)(F)C(O)=O.N1C2C(=CC=CC=2C(C2C=CC=CC=2)CCNC)C=C1>>[CH3:8][O:9][C:10]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][C:17]=2[CH:19]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[CH2:20][CH2:21][NH:23][CH3:24])[NH:12][N:11]=1

Participants

5

Reactant 4

HCID 6422Trifluoroacetic acidHCID 84468TrifluoroacetateHCID 17747555[3-(1H-Indol-7-yl)-3-phenyl-propyl]-methyl-amineHCID 59831778HCID 59831778, compound

Product 1

HCID 59831768HCID 59831768, compound

Procedure

[3-(3-Methoxy-1H-indazol-4-yl)-3-phenyl-propyl]-methyl-amine CXC was prepared as a trifluoroacetate from 3-(3-methoxy-1H-indazol-4-yl)-N-methyl-3-phenyl-propionamide and trifluoroacetic acid, using the procedure described for preparation of [3-(1H-Indol-7-yl)-3-phenyl-propyl]-methyl-amine XX (Example 4). MS (M+H)=297.

Sources & evidence

ORD record
ord-f26ec988e6004dd2ad883abaf8bfe23e
Source dataset
uspto-grants-2010_09
Patent number
US07803830B2

Reaction notes

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