Trifluoroacetic acid → HCID 59831630, compound

HRID 1716770Notes

Reaction equation

HRID 1716770 reaction equation
[CH3:1][O:2][C:3]1[C:11]2[C:6](=[CH:7][C:8]([CH:12]([C:18]3[CH:19]=[N:20][CH:21]=[CH:22][CH:23]=3)[CH2:13][C:14]([NH:16][CH3:17])=O)=[CH:9][CH:10]=2)[NH:5][N:4]=1.C(O)(C(F)(F)F)=O.N1C2C(=CC=CC=2C(C2C=CC=CC=2)CCNC)C=C1>>[CH3:1][O:2][C:3]1[C:11]2[C:6](=[CH:7][C:8]([CH:12]([C:18]3[CH:19]=[N:20][CH:21]=[CH:22][CH:23]=3)[CH2:13][CH2:14][NH:16][CH3:17])=[CH:9][CH:10]=2)[NH:5][N:4]=1

Participants

4

Reactant 3

HCID 6422Trifluoroacetic acidHCID 17747555[3-(1H-Indol-7-yl)-3-phenyl-propyl]-methyl-amineHCID 59831849HCID 59831849, compound

Product 1

HCID 59831630HCID 59831630, compound

Procedure

[3-(3-Methoxy-1H-indazol-6-yl)-3-pyridin-3-yl-propyl]-methyl-amine CCLI was prepared from 3-(3-methoxy-1H-indazol-6-yl)-N-methyl-3-pyridin-3yl-propionamide and TFA using the procedure described for preparation of [3-(1H-Indol-7-yl)-3-phenyl-propyl]-methyl-amine XX (Example 4). MS (M+H)=298.

Sources & evidence

ORD record
ord-0a6312ea131a491faf06b47886af8649
Source dataset
uspto-grants-2010_09
Patent number
US07803830B2

Reaction notes

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