反应详情

5-Bromo-2-fluoro-benzoic acid (250 mg, 1.14 mmol) was coupled to aniline (64) (245 mg, 1.25 mmol) using Method D. The residue was purified by column chromatography eluting with a stepped gradient of 10-15% EtOAc in heptane to give the title compound.

1. customThe residue was purified by column chromatography
2. washeluting with a stepped gradient of 10-15% EtOAc in heptane