Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl 3-(3-Aminophenyl)propionate → 3-(3-{[6-(4-Fluoro-phenyl)-pyridine-2-carbonyl]amino}-phenyl)-propionic acid ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl 3-(3-Aminophenyl)propionate | HCID 82314 | — |
| 반응물 | 6-(4-Fluorophenyl)picolinic acid | HCID 21081708 | — |
| 생성물 | 3-(3-{[6-(4-Fluoro-phenyl)-pyridine-2-carbonyl]amino}-phenyl)-propionic acid ethyl ester | HCID 59654758 | — |
반응 단계
Carboxylic acid (152) (50 mg, 0.23 mmol) was coupled to aniline (124) (45 mg, 0.23 mmol) using Method C. The residue was purified by column chromatography eluting with 30% EtOAc in heptane to give the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07803841B2 |
| 출처 데이터셋 | uspto-grants-2010_09 |
| ORD ID | ord-6645fed6bf7d44adbe4590ee9b2fd6ec |
| 출처 메모 | uspto-grants-2010_09 |