Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1717520Generated: November 1, 2026

N-(5-fluoro-2-phenoxyphenyl)acetamide → N-[2-(2-Allyloxy-ethoxy)-5-methoxy-benzyl]-N-(5-fluoro-2-phenoxy-phenyl)-acetamide

https://huagongshe.com/reaction/1717520

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(5-fluoro-2-phenoxyphenyl)acetamideHCID 44126830—
Reactant1-(2-Allyloxy-ethoxy)-2-bromomethyl-4-methoxy-benzeneHCID 67104042—
ProductN-[2-(2-Allyloxy-ethoxy)-5-methoxy-benzyl]-N-(5-fluoro-2-phenoxy-phenyl)-acetamideHCID 2478555549%

Reaction Steps

The general procedure C was applied to N-(5-Fluoro-2-phenoxy-phenyl)-acetamide and 10b The desired product 10c was obtained in 49% yield (4.9 mmol; 2.28 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07803960B2
Source datasetuspto-grants-2010_09
ORD IDord-08b6c0e97f3c47ad8bcb6965be15f53c
Source noteuspto-grants-2010_09