Dimethyl Sulfoxide → 2-(4-(1,3-Dioxan-2-yl)-2-fluorophenyl)-5-(1-cyclobutyl-cyclopropyl)thiazolo[5,4-b]pyridine
Reaction equation
[CH2:41]1[O:42][CH2:43][CH2:44][CH2:45]1.[CH3:30][S+:31]([CH3:32])([CH3:33])=[O:34].[CH3:35][C:36]([O-:37])([CH3:38])[CH3:39].[CH3:46][S:47]([CH3:48])=[O:49].[I-:29].[K+:40].[O:1]1[CH:2]([c:7]2[cH:8][c:9]([F:28])[c:10](-[c:13]3[s:14][c:15]4[n:16][c:17]([C:22](=[CH2:23])[CH:24]5[CH2:25][CH2:26][CH2:27]5)[cH:18][cH:19][c:20]4[n:21]3)[cH:11][cH:12]2)[O:3][CH2:4][CH2:5][CH2:6]1>>[O:1]1[CH:2]([c:7]2[cH:8][c:9]([F:28])[c:10](-[c:13]3[s:14][c:15]4[n:16][c:17]([C:22]5([CH:24]6[CH2:25][CH2:26][CH2:27]6)[CH2:23][CH2:30]5)[cH:18][cH:19][c:20]4[n:21]3)[cH:11][cH:12]2)[O:3][CH2:4][CH2:5][CH2:6]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-f163eff11ea14d5e81c6fa6ca30bd9dc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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