HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-acetyl-S-(2-aminophenyl)cysteine → 5,1-Benzothiazepine-2-one, 3-acetylamino-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-acetyl-S-(2-aminophenyl)cysteine | HCID 57145208 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | 5,1-Benzothiazepine-2-one, 3-acetylamino- | HCID 539362 | 71.7% |
Reaction Steps
1.2 g of N-acetyl-S-(2-aminophenyl)cysteine was dissolved in 20 ml of xylene and the resulting solution was heated under reflux for 2 hours. After cooling, the precipitated crystals were separated and washed with methanol to obtain 0.8 g of the desired compound, or 3-acetylamino-2,3-dihydro-1,5-benzothiazepin-4(5H)-one. Its melting point was 283°-286° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04539151 |
| Source dataset | uspto-grants-1985_09 |
| ORD ID | ord-69814e6d39a44174a436f6162e7f9839 |
| Source note | uspto-grants-1985_09 |