Hydrochloric Acid → HCID 13454590, compound

Participants

Reaction Steps

1.25 g of the 3-ethoxycarbonylmethylamino- 5-t-butoxy-2,3-dihydro-1,5-benzothiazepin-4(5H)-one obtained in Example 14 was dissolved in 10 ml of a 6N solution of hydrogen chloride in dioxane and then reacted at room temperature for an hour. After this solution was concentrated under reduced pressure, ether was added thereto so as to cause crystallization. Thus, there was obtained 720 mg of the desired compound. When heated to determine its melting point, this compound decomposed at 248° C.

Provenance & Evidence