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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1719232Generated: October 30, 2026

HCID 13251293, compound → 6-Trifluoromethylisatin

https://huagongshe.com/reaction/1719232

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 13251293HCID 13251293—
ReactantHCID 13251297HCID 13251297—
Product6-TrifluoromethylisatinHCID 10987649—
Product4-Bromo-1-(bromomethyl)-2-chlorobenzeneHCID 21914486—

Reaction Steps

(Example 5): 1'-(2-chloro-4-bromobenzyl)-6'-trifluoromethyl-spiro[imidazolidine-4,3'-indoline]-2,2',5-trione, as a solid, m.p. 299°-301° C., starting from 1-(2-chloro-4-bromobenzyl)-6-trifluoromethylindoline-2,3-dione (itself obtained as a solid, m.p. 132°-134° C., by reaction of 2-chloro-4-bromobenzyl bromide with 6-trifluoromethylindoline-2,3-dione in an analogous manner to that described for the starting material in Example 1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04539329
Source datasetuspto-grants-1985_09
ORD IDord-97f798d7bbc9499f9193e6d5bf1d9925
Source noteuspto-grants-1985_09