HRID1719240

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID108578

2(1H)-Pyrimidinone, 5-chloro-

C4H3ClN2O

HCID10921254

未命名化合物

PRODUCTS

生成物

HCID15650493

5-Chloro-1-{[(4-methoxyphenyl)methoxy]methyl}pyrimidin-2(1H)-one

C13H13ClN2O3

收率 52%

PROCEDURE

实验过程

was prepared as described in Example 3 from chloromethyl 4-methoxybenzyl ether (see Preparation 4a and 4b) (10 mmol) and 5-chloropyrimidin-2-one (10 mmol) in 52% yield (1.45 g), m.p. 118° C. 1H NMR (CDCl3): δ3.77 (OMe), 4.57 (CH2Ph), 5.27 (CH2O), 6.6-7.3 (Ph), 7.63 and 8.35 (H-4, H-6, J 4 Hz). IR(KBr): 1670 cm1 (CO).

WORKUP

后处理

customwas prepared