反应详情

was prepared as described in Example 3 from chloromethyl 3-trifluoromethyl-benzyl ether (see Preparation 6a and 6b) (10 mmol) and 5-chloropyrimidin-2-one hydrochloride (10 mmol) in 52%. (1.66 g) yield, m.p. 95° C. 1H NMR (CDCl3): δ4.77 (CH2Ph), 5.42 (CH2O), 7.3-7.7 (Ph), 7.82 and 8.55 (H-4, H-6, J 4 Hz). IR(KBr): 1660 cm-1 (CO).

1. customwas prepared
2. custom(1.66 g) yield