Hydrochloric Acid → HCID 178447643, compound

HRID 1719594Notes

Reaction equation

HRID 1719594 reaction equation
Cl.[CH3:2][N:3]1[C:7]([CH:8]([CH3:15])[CH2:9][CH2:10][C:11]([O:13]C)=[S:12])=[N:6][N:5]=[N:4]1>O>[CH3:2][N:3]1[C:7]([CH:8]([CH3:15])[CH2:9][CH2:10][C:11]([OH:13])=[S:12])=[N:6][N:5]=[N:4]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 54172935Methyl 4-(1-methyl-1,2,3,4-tetrazol-5-yl)thiovalerate

Product 1

HCID 178447643HCID 178447643, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

20% aqueous Hydrochloric acid (150 ml) is added to methyl 4-(1-methyl-1,2,3,4-tetrazol-5-yl)thio-valerate (17 g) and the mixture is refluxed for 2 hours. After cooling, the reaction mixture is diluted with water and extracted with chloroform. The chloroform solution is washed with aqueous saturated sodium chloride solution and dried over magnesium sulfate. Chloroform is distilled off to give 4-(1-methyl-1,2,3,4-tetrazol-5-yl)thio-valeric acid, colorless liquid, nD26 =1.5133.

Workup

  1. temperaturethe mixture is refluxed for 2 hours
  2. temperatureAfter cooling
  3. extractionextracted with chloroform
  4. washThe chloroform solution is washed with aqueous saturated sodium chloride solution
  5. dry with materialdried over magnesium sulfate
  6. distillationChloroform is distilled off

Sources & evidence

ORD record
ord-06d2c0b3fad040ff9ba35b2d2cd3d511
Source dataset
uspto-grants-1985_09
Patent number
US04540703

Reaction notes

Loading…