2-Propanone, 1-nitro- → HCID 13374890, compound

HRID 1719616Notes

Reaction equation

HRID 1719616 reaction equation
[C:1]1([C:7]2[O:8][C:9]3[C:14]([C:15](=[O:17])[CH:16]=2)=[CH:13][CH:12]=[CH:11][C:10]=3[CH:18]=O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:20]/[C:21](/[CH3:27])=[CH:22]\[C:23]([O:25][CH3:26])=[O:24].[N+:28]([CH2:31][C:32](=O)[CH3:33])([O-:30])=[O:29]>CCO>[CH3:27][C:21]1[NH:20][C:32]([CH3:33])=[C:31]([N+:28]([O-:30])=[O:29])[CH:18]([C:10]2[CH:11]=[CH:12][CH:13]=[C:14]3[C:9]=2[O:8][C:7]([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)=[CH:16][C:15]3=[O:17])[C:22]=1[C:23]([O:25][CH3:26])=[O:24]

Participants

5

Reactant 3

HCID 662962-Propanone, 1-nitro-HCID 643918Methyl 3-aminocrotonateHCID 13233926HCID 13233926, compound

Product 1

HCID 13374890HCID 13374890, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

10 mmol each of 2-phenyl-4-oxo-4H-chromen-8-aldehyde, methyl 3-aminocrotonate and nitroacetone are boiled under reflux in 20 ml of absolute EtOH for 3 hours, the mixture is concentrated and the residue is crystallized from methanol.

Workup

  1. concentrationthe mixture is concentrated
  2. customthe residue is crystallized from methanol

Sources & evidence

ORD record
ord-a8e37e6cea9f452f86037ad85d0c0307
Source dataset
uspto-grants-1985_09
Patent number
US04540789

Reaction notes

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