Hydrochloric Acid → HCID 131714324, compound

Participants

Reaction Steps

13-Amino-5,6,7,8,9,10,11,12-octahydro-5-methyl-5,11-methanobenzocyclodecen-3,12-diol (0.7 g., 0.002 mole) was dissolved in 20 mL of boiling ethanol. To this solution was added 5 mL ethanol saturated with hydrogen chloride and was allowed to stand overnight. The solvent was evaporated under reduced pressure and the resulting residue was recrystallized from acetone-ethanol (5:1) to afford 400 mg (70% yield) of the title compound as a hydrochloride hemihydrate, mp 216°-218° C.

Provenance & Evidence