HCID 53824855, compound → HCID 20266259, compound

Participants

Reaction Steps

To a solution of 2.84 g of 3-(4-phenylthiobenzoyl)acrylic acid in 30 ml of chloroform was added 0.8 ml of thioacetic acid, and the resulting mixture was stirred for 5 hours at room temperature. The chloroform was removed from the mixture by evaporation under reduced pressure, and the residue was purified by silica gel column chromatography (eluent: hexane-ethyl acetate) and then recrystallized from a mixture of hexane and ethyl acetate to give 3.24 g of 2-acetylthio-3-(4-phenylthiobenzoyl)propionic acid.

Provenance & Evidence