HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 20266533, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 3-Chlorobenzo(b)thiophene-2-carbonyl chloride | HCID 519898 | — |
| Reactant | 2-(1H-1,2,4-triazol-1-yl)ethan-1-amine dihydrochloride | HCID 20248317 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 20266533 | HCID 20266533 | — |
Reaction Steps
A mixture of about 1.85 g of 1H-1,2,4-triazole-1ethanamine dihydrochloride, about 50 ml of methylene chloride, about 30 ml of 1N sodium hydroxide and about 2.3 g of 3-chlorobenzo-[b]thiophene carbonyl chloride was stirred for about 16 hours. A 50 ml portion of methylene chloride and about 5 ml of 1N sodium hydroxide were added and the layers were separated. The organic layer was washed twice with water dried and concentrated, giving the desired compound, mp 151°-152° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04542145 |
| Source dataset | uspto-grants-1985_09 |
| ORD ID | ord-a92851b8014b407a8efc7ee0a115814c |
| Source note | uspto-grants-1985_09 |