反应详情

温度

50 °C

10 g of 3-phenyl-5-chlorooxindole were dissolved in 100 ml of acetone and 20 ml of water, 2.9 g of potassium carbonate and 2.9 ml of methyl iodide were added and the mixture was warmed at 50° C. for 3 hours and concentrated; water was added to the residue, which was extracted with ethyl acetate, and the extract was dried over magnesium sulfate, and the solvent was removed. The residue was recrystallized from ethanol. Melting point 180°-181° C.

1. concentrationconcentrated
2. additionwater was added to the residue, which
3. extractionwas extracted with ethyl acetate
4. dry with materialthe extract was dried over magnesium sulfate
5. customthe solvent was removed
6. customThe residue was recrystallized from ethanol