反应详情

N-Benzyl-N-butylamine hydrochloride (12 g), 6 ml of 37% formalin, 40 ml of acetic anhydride and 11.5 g of 6-methyl-1,2,3,4,7,8,9,10-octahydro-benzo[f]quinoline-3,10-dione are allowed to react and post-treated in the same manner of Example 1. The obtained crystals are recrystallized from isopropanol to give 13.2 g of 9-(N-benzyl-N-butylaminomethyl)-6-methyl-1,2,3,4,7,8,9,10-octahydro-benzo[f]quinoline-3,10-dione as colorless needles, melting at 190°-193° C.

1. customto react
2. additionpost-treated in the same manner of Example 1
3. customThe obtained crystals are recrystallized from isopropanol