HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formaldehyde → 9-(N-benzyl-N-butylaminomethyl)-6-methyl-1,2,3,4,7,8,9,10-octahydro-benzo[f]quinoline-3,10-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | N-benzylbutan-1-amine Hydrochloride | HCID 176997 | — |
| Reactant | 6-Methyl-1,2,3,4,7,8,9,10-octahydro-benzo[f]quinoline-3,10-dione | HCID 13051767 | — |
| Solvent | Acetic Anhydride | HCID 7918 | — |
| Product | 9-(N-benzyl-N-butylaminomethyl)-6-methyl-1,2,3,4,7,8,9,10-octahydro-benzo[f]quinoline-3,10-dione | HCID 13324447 | — |
Reaction Steps
N-Benzyl-N-butylamine hydrochloride (12 g), 6 ml of 37% formalin, 40 ml of acetic anhydride and 11.5 g of 6-methyl-1,2,3,4,7,8,9,10-octahydro-benzo[f]quinoline-3,10-dione are allowed to react and post-treated in the same manner of Example 1. The obtained crystals are recrystallized from isopropanol to give 13.2 g of 9-(N-benzyl-N-butylaminomethyl)-6-methyl-1,2,3,4,7,8,9,10-octahydro-benzo[f]quinoline-3,10-dione as colorless needles, melting at 190°-193° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04543354 |
| Source dataset | uspto-grants-1985_09 |
| ORD ID | ord-b0eebc3e299b4f27b8175d8ab3270e60 |
| Source note | uspto-grants-1985_09 |