Hydrochloric Acid → 2-Chloro-4-morpholinothieno[3,2-d]pyrimidine-6-carbonitrile

HRID 171996Notes

Reaction equation

HRID 171996 reaction equation
[Cl:1][c:2]1[n:3][c:4]([N:12]2[CH2:13][CH2:14][O:15][CH2:16][CH2:17]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([I:11])[s:10]2.[ClH:21].[Cu:18][C:19]#[N:20].[cH:22]1[cH:23][cH:24][n:25][cH:26][cH:27]1>>[Cl:1][c:2]1[n:3][c:4]([N:12]2[CH2:13][CH2:14][O:15][CH2:16][CH2:17]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([C:19]#[N:20])[s:10]2

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 1049PyridineHCID 595930614-(2-Chloro-6-iodothieno[3,2-d]pyrimidin-4-yl)morpholineHCID 178418546HCID 178418546, compound

Product 1

HCID 866184522-Chloro-4-morpholinothieno[3,2-d]pyrimidine-6-carbonitrile

Sources & evidence

ORD record
ord-903bc736f74b4c2c94825293fc9a49b4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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