反应详情

温度

-5 °C

To a 65 g sample of 1,2-diamino-2-methylpropane dissolved in 650 mL of toluene cooled to -5° C. was added dropwise over 45 minutes a toluene solution (200 mL) of benzylchloroformate (52 g, 1.18 mmol). The reaction was warmed to room temperature and stirred for 2 hours before it was filtered and the filtrate was stripped of all solvent under reduced pressure. The residue, dissolved in CH2Cl2 (100 mL), was filtered and the filtrate again was stripped of all solvent to produce the title compound (54 g) as a viscous oil.

1. temperatureThe reaction was warmed to room temperature
2. filtrationwas filtered
3. dissolutionThe residue, dissolved in CH2Cl2 (100 mL)
4. filtrationwas filtered