Succinic anhydride → 4-Oxo-4-(4-pentylphenyl)butanoic acid

HRID 1720139Notes

Reaction equation

HRID 1720139 reaction equation
[C:1]1(=[O:7])[O:6][C:4](=[O:5])[CH2:3][CH2:2]1.[Cl-].[Al+3].[Cl-].[Cl-].[CH2:12]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)[CH2:13][CH2:14][CH2:15][CH3:16]>>[CH2:12]([C:17]1[CH:18]=[CH:19][C:20]([C:1]([CH2:2][CH2:3][C:4]([OH:6])=[O:5])=[O:7])=[CH:21][CH:22]=1)[CH2:13][CH2:14][CH2:15][CH3:16]

Participants

4

Reactant 3

HCID 7922Succinic anhydrideHCID 10864PentylbenzeneHCID 6451240Aluminum(III) Chloride

Product 1

HCID 20632464-Oxo-4-(4-pentylphenyl)butanoic acid

Procedure

Succinic anhydride (8.6 g; 0.1 mole) is reacted with pentylbenzene (100 ml) and aluminum chloride (29 g; 0.22 mole) and the product isolated by the manner described in Example 3. Recrystallization from aqueous ethanol gives 3-(4-n-pentylbenzoyl)propanoic acid (17 g) as colorless crystals, m.p. 98°-100° C.

Workup

  1. customthe product isolated by the manner
  2. customRecrystallization from aqueous ethanol

Sources & evidence

ORD record
ord-b648181de95f4710a769cec70c4b1e09
Source dataset
uspto-grants-1996_04
Patent number
US05504244

Reaction notes

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