3-Hydroxy-2-nitrovaleric acid ethyl ester → HCID 53662264, compound

HRID 1720324Notes

Reaction equation

HRID 1720324 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[N:7]=[CH:8][C:9]2[NH:10][C:11]3[C:16]([C:17]=2[C:18]=1[CH2:19]C)=[C:15]([CH2:21]C1C=CC(Cl)=CC=1)[CH:14]=[CH:13][CH:12]=3)=[O:5])[CH3:2].[Cl:29][C:30]1[CH:45]=[CH:44][C:33](CC2C=C3C(=CC=2)NC=C3)=[CH:32][CH:31]=1.[CH2:46]([O:48]C(=O)C([N+]([O-])=O)C(O)CC)C>C(OCC)(=O)C>[CH2:1]([O:3][C:4]([C:6]1[N:7]=[CH:8][C:9]2[NH:10][C:11]3[C:16]([C:17]=2[C:18]=1[CH2:19][O:48][CH3:46])=[C:15]([CH2:21][C:31]1[CH:32]=[CH:33][CH:44]=[CH:45][C:30]=1[Cl:29])[CH:14]=[CH:13][CH:12]=3)=[O:5])[CH3:2]

Participants

5

Reactant 3

HCID 145311763-Hydroxy-2-nitrovaleric acid ethyl esterHCID 224177025-(4-Chlorobenzyl)-indoleHCID 541204915-(4-Chlorobenzyl)-4-ethyl-beta-carboline-3-carboxylic acid ethyl ester

Product 1

HCID 53662264HCID 53662264, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

5-(4-chlorobenzyl)-4-ethyl-β-carboline-3-carboxylic acid ethyl ester from 5-(4-chlorobenzyl)-indole and 3-hydroxy-2-nitrovaleric acid ethyl ester, melting point 265° C. (ethyl acetate);

Sources & evidence

ORD record
ord-6e0031290e754b3581ba1ba0007ad0e0
Source dataset
uspto-grants-1996_04
Patent number
US05506234

Reaction notes

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