Thioglycerol → HCID 10537793, compound

Participants

Reaction Steps

Acrylic acid t-butyl ester (15 g) and thioglycerol (15 g) were mixed together in the absence of solvent. To the reaction mixture, one drop of triethylamine was added to cause an exothermic reaction, yielding a homogeneous reaction mixture, which was then diluted with ethyl acetate, washed with water and dried, followed by solvent concentration under reduced pressure, to yield the title compound (25.79 g, yield 93%) as a colorless oily substance.

Provenance & Evidence