HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → (6,7-Bis(palmitoyloxy),4-thiaheptanoyl)glycylglycine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 1-(Oxiran-2-yl)ethan-1-ol | HCID 11593431 | — |
| Reactant | (6,7-Bis(palmitoyloxy)-4-thiaheptanoyl)glycylglycine t-butyl ester | HCID 22418588 | — |
| Product | (6,7-Bis(palmitoyloxy),4-thiaheptanoyl)glycylglycine | HCID 22353662 | 100% |
Reaction Steps
To (6,7-bis(palmitoyloxy)-4-thiaheptanoyl)glycylglycine t-butyl ester as obtained in Example 3 (190 mg), trifiuoroacetic acid (2 ml) was added, followed by stirring at room temperature for I hour. The mixture was concentrated to yield the title compound (178 mg, yield 100%) as a colorless crystal.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05506267 |
| Source dataset | uspto-grants-1996_04 |
| ORD ID | ord-07334b6b527449bfa0c585077a279f1e |
| Source note | uspto-grants-1996_04 |