Epichlorohydrin → Acetophenone, 2',2'''-(2-hydroxytrimethylenedioxy)bis(6-hydroxy-

HRID 1721144Notes

Reaction equation

HRID 1721144 reaction equation
[CH3:1][C:2]([C:4]1[C:5]([OH:11])=[CH:6][CH:7]=[CH:8][C:9]=1[OH:10])=[O:3].[CH2:12]([CH:14]1[O:16][CH2:15]1)Cl.[OH-:17].[K+]>C(O)(C)C>[C:2]([C:4]1[C:9]([OH:10])=[CH:8][CH:7]=[CH:6][C:5]=1[O:11][CH2:1][CH:2]([OH:3])[CH2:4][O:17][C:5]1[CH:6]=[CH:7][CH:8]=[C:9]([OH:10])[C:12]=1[C:14](=[O:16])[CH3:15])(=[O:3])[CH3:1]

Participants

5

Reactant 3

HCID 7835EpichlorohydrinHCID 14797Potassium HydroxideHCID 696872',6'-Dihydroxyacetophenone

Product 1

HCID 85303Acetophenone, 2',2'''-(2-hydroxytrimethylenedioxy)bis(6-hydroxy-

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

reacting 2,6-dihydroxyacetophenone with epichlorohydrin in the presence of potassium hydroxide and isopropanol to form 1,3-bis(2-acetyl-3-hydroxyphenoxy)-2-hydroxypropane;

Sources & evidence

ORD record
ord-1b04850631b04e1ebda7ea4f31446af3
Source dataset
uspto-grants-1996_04
Patent number
US05508451

Reaction notes

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