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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1721187Generated: October 30, 2026

2,2-Dimethylsuccinic anhydride → 4-[3-(7-Fluoro-2-quinolinylmethoxy)phenylamino]-2,2-dimethyl-4-oxobutanoic acid

https://huagongshe.com/reaction/1721187

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,2-Dimethylsuccinic anhydrideHCID 87067—
Reactant3-(7-Fluoro-2-quinolinylmethoxy)anilineHCID 22416872—
Product4-[3-(7-Fluoro-2-quinolinylmethoxy)phenylamino]-2,2-dimethyl-4-oxobutanoic acidHCID 22416903—

Reaction Steps

The title compound is prepared analogously to the compound described in Example 20 from 2,2-dimethylsuccinic acid anhydride and 3-(7-fluoro-2-quinolinylmethoxy)aniline; colourless crystals of m.p. 209°-210°.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05508408
Source datasetuspto-grants-1996_04
ORD IDord-d1fa32135de046898af85b3c1464cc5b
Source noteuspto-grants-1996_04