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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1721188Generated: November 1, 2026

2-Ethyl-2-methylsuccinic anhydride → 4-[3-(7-Fluoro-2-quinolinylmethoxy)phenylamino]-2-ethyl-2-methyl-4-oxobutanoic acid

https://huagongshe.com/reaction/1721188

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Ethyl-2-methylsuccinic anhydrideHCID 3016533—
Reactant3-(7-Fluoro-2-quinolinylmethoxy)anilineHCID 22416872—
Product4-[3-(7-Fluoro-2-quinolinylmethoxy)phenylamino]-2-ethyl-2-methyl-4-oxobutanoic acidHCID 22416883—

Reaction Steps

The title compound is prepared analogously to the compound described in Example 20 from 2-ethyl-2-methylsuccinic acid anhydride and 3-(7-fluoro-2-quinolinylmethoxy)aniline; colourless crystals of m.p. 179°-180°.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05508408
Source datasetuspto-grants-1996_04
ORD IDord-615aa3c442704ab2a7a02e932bb9a75c
Source noteuspto-grants-1996_04