Pyrrolidine → HCID 19428512, compound

HRID 1721301Notes

Reaction equation

HRID 1721301 reaction equation
[CH:1]1([NH:6][C:7]2[N:12]=[C:11](Cl)[CH:10]=[C:9]([Cl:14])[N:8]=2)[CH2:5][CH2:4][CH2:3][CH2:2]1.[NH:15]1[CH2:19][CH2:18][CH2:17][CH2:16]1>>[CH:1]1([NH:6][C:7]2[N:8]=[C:9]([Cl:14])[CH:10]=[C:11]([N:15]3[CH2:19][CH2:18][CH2:17][CH2:16]3)[N:12]=2)[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

3

Reactant 2

HCID 31268PyrrolidineHCID 19428501HCID 19428501, compound

Product 1

HCID 19428512HCID 19428512, compoundYield 72.4%

Procedure

The reaction of 2-cyclopentylamino-4,6-dichloropyrimidine with pyrrolidine as described in Example 13 gives the title compound as an oily product in a yield of 72.4%.

Sources & evidence

ORD record
ord-c2d2304064034e0c832b908526fd7f51
Source dataset
uspto-grants-1996_04
Patent number
US05510345

Reaction notes

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