HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroacetone → HCID 24755240, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroacetone | HCID 6571 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | 4-Methoxybenzenethiol | HCID 12765 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Product | HCID 24755240 | HCID 24755240 | — |
Reaction Steps
0.165 Mol sodium hydride is added portionwise at 0° to a solution of 4-methoxy-thiophenol (0.15 mol) in 300 ml THF. After 1 hour chloracetone (0.165 mol) is added. The mixture is stirred overnight at room temperature. Thereafter the solvent is evaporated and the mixture is dissolved in CH2Cl2 and washed with 2 N Na2CO3. The organic phase is dried and the solvent is evaporated to yield the title a) compound which is used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05510353 |
| Source dataset | uspto-grants-1996_04 |
| ORD ID | ord-8bb8c1da78e4457c899d1dbe41ae5470 |
| Source note | uspto-grants-1996_04 |