Propofol → HCID 53922406, compound

Participants

Reaction Steps

The general procedure of Example I(A) was followed to react ethyl chlorosulfonylacetate with 2,6-diisopropylphenol to give ethyl (2,6-diisopropylphenoxysulfonyl)acetate. The ethyl acetate derivative was hydrolyzed to 2,6-diisopropylphenoxysulfonyl acetic acid. The acetic acid derivative was reacted with dodecylamine and DCC according to Example I(B) to provide 2,6-diisopropylphenyl N-dodecylcarbamoylmethylsulfonate, mp 75°-78° C.

Provenance & Evidence