Carbon Tetrachloride → HCID 85664896, compound

HRID 1721566Notes

Reaction equation

HRID 1721566 reaction equation
[CH:1]([O:4][NH:5][C:6](=O)[C:7]1[CH:12]=[CH:11][CH:10]=[C:9]([CH2:13][CH2:14][CH:15]([CH3:17])[CH3:16])[CH:8]=1)([CH3:3])[CH3:2].C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C(Cl)(Cl)(Cl)[Cl:39]>C(#N)C>[CH:1]([O:4][N:5]=[C:6]([Cl:39])[C:7]1[CH:12]=[CH:11][CH:10]=[C:9]([CH2:13][CH2:14][CH:15]([CH3:17])[CH3:16])[CH:8]=1)([CH3:3])[CH3:2]

Participants

5

Reactant 3

HCID 5943Carbon TetrachlorideHCID 11776TriphenylphosphineHCID 22413304HCID 22413304, compound

Product 1

HCID 85664896HCID 85664896, compoundYield 88%

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

To 200 ml of acetonitrile were added 5.4 g (23.5 mmol) of O-isopropyl 3-isopentylbenzohydroxamic acid, 9.9 g (37.8 mmol) of triphenylphosphine, and 11.6 g (75.3 mmol) of carbon tetrachloride. The mixture was refluxed for 1 hour. The refluxed mixture was allowed to sit and cool naturally, and the solvent in the mixture was removed under reduced pressure. The residue was purified by column chromatography, thus obtaining the desired product of 5.1 g (yield: 88%).

Workup

  1. temperatureThe mixture was refluxed for 1 hour
  2. temperaturecool naturally
  3. customthe solvent in the mixture was removed under reduced pressure
  4. customThe residue was purified by column chromatography

Sources & evidence

ORD record
ord-db8880b133044ae49520dd219b072280
Source dataset
uspto-grants-1996_04
Patent number
US05512551

Reaction notes

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