HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,5-Dichloropyrazine → 2-Chloro-5-(4-benzyloxyphenyl)pyrazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,5-Dichloropyrazine | HCID 336224 | — |
| Reactant | 4-Benzyloxy-phenylboronic acid | HCID 2734314 | — |
| Product | 2-Chloro-5-(4-benzyloxyphenyl)pyrazine | HCID 53878793 | — |
Reaction Steps
In accordance with scheme C-I, 30 g (201 mmol) of 2,5-dichloropyrazine and 45.92 g (201 mmol) of 4-benzyloxyphenylboronic acid are coupled analogously to Example 4a to give 2-chloro-5-(4-benzyloxyphenyl)pyrazine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05512207 |
| Source dataset | uspto-grants-1996_04 |
| ORD ID | ord-37353ad561064ec8abb31eda9b64e040 |
| Source note | uspto-grants-1996_04 |