Hydrochloric Acid → HCID 13851912, compound

Participants

Reaction Steps

A solution of 3.5 g. (mmol) 6-[N-benzyl-N-(2-propyl)-amino]-9-ribofuranosylpurine and 50 ml. 2N hydrochloric acid is heated under reflux for 30 minutes. After cooling, it is washed with diethyl ether, the aqueous phase is adjusted to pH 7 with aqueous ammonia solution and the precipitate is recrystallized from aqueous propan-2-ol. There is obtained 1.8 g. of the title compound (75% of theory); m.p. 200°-202° C.

Provenance & Evidence