反应详情

1.67 g of 2,3-dichloro-4-(1-ethoxymethyl-5-pyrazolylcarbonyl)phenol, 1.15 g of ethyl bromoacetate and 1.68 g of potassium carbonate are added to 60 ml of acetone, and the mixture is refluxed for 1 hour. The reaction mixture is filtered and the filtrate is evaporated to remove solvent. The residue is dissolved in benzene, and the solution is treated with activated charcoal and evaporated to give an oil, which is then crystallized from isopropyl ether to give 1.89 g of ethyl [2,3-dichloro-4-(1-ethoxymethyl-5-pyrazolylcarbonyl)phenoxy]acetate.

1. temperaturethe mixture is refluxed for 1 hour
2. filtrationThe reaction mixture is filtered
3. customthe filtrate is evaporated
4. customto remove solvent
5. dissolutionThe residue is dissolved in benzene
6. additionthe solution is treated with activated charcoal
7. customevaporated
8. customto give an oil, which
9. customis then crystallized from isopropyl ether