Tert-Butylamine → 1-[4-{-2-(1,1-Dimethylethylamino)-ethoxy}-phenyl]-ethanone

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

A mixture of 6.5 g of the product of Step A in 30 ml of tert.-butylamine was heated at 120° C. for 30 hours and was then diluted with water and extracted with ethyl acetate. The organic phase was washed with water, dried over a deshydrant, filtered and evaporated to dryness. The residue was chromatographed over silica and eluted with a 9-1 ethyl acetate-triethylamine mixture to obtain 7.264 g of 1-[4-{-2-(1,1-dimethylethylamino)-ethoxy}-phenyl]-ethanone.

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