Hydrochloric Acid → 5-Bromo-1-methyl-3-((5-(piperazin-1-yl)-pyridin-2-yl)amino)pyridin-2(1H)-one

HRID 172215Notes

Reaction equation

HRID 172215 reaction equation
[Br:1][c:2]1[cH:3][c:4]([NH:10][c:11]2[cH:12][cH:13][c:14]([N:17]3[CH2:18][CH2:19][N:20]([C:23]([O:24][C:25]([CH3:26])([CH3:27])[CH3:28])=[O:29])[CH2:21][CH2:22]3)[cH:15][n:16]2)[c:5](=[O:9])[n:6]([CH3:8])[cH:7]1.[ClH:30].[O:31]1[CH2:32][CH2:33][O:34][CH2:35][CH2:36]1>>[Br:1][c:2]1[cH:3][c:4]([NH:10][c:11]2[cH:12][cH:13][c:14]([N:17]3[CH2:18][CH2:19][NH:20][CH2:21][CH2:22]3)[cH:15][n:16]2)[c:5](=[O:9])[n:6]([CH3:8])[cH:7]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 58043929Tert-butyl 4-(6-((5-bromo-1-methyl-2-oxo-1,2-dihydropyridin-3-yl)amino)pyridin-3-yl)piperazine-1-carboxylate

Product 1

HCID 580436655-Bromo-1-methyl-3-((5-(piperazin-1-yl)-pyridin-2-yl)amino)pyridin-2(1H)-one

Sources & evidence

ORD record
ord-c531b2b41cee412c928854260bb0c911
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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