HRID1722490

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C(=O)O[C@@H]2O[C@H](C(=O)O)[C@@H](O)[C@H](O)[C@H]2O)C(C)(C)CCC1

HCID5281877

Retinoyl beta-glucuronide

C26H36O8

结构：CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C(=O)F)C(C)(C)CCC1

HCID5378594

未命名化合物

PRODUCTS

生成物

结构：O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)C(=O)O

HCID65041

未命名化合物

PROCEDURE

实验过程

The first chemical synthesis of retinoyl β-glucuronide was reported by us (Barua & Olson, J. Lipid Res. 26: 1277-1282, 1985), and involves a two-step procedure. Retinoyl fluoride was allowed first to react with 6,3-glucuronolactone to produce the 6,3-lactone of retinoyl glucuronic acid, which was then hydrolysed with very dilute alkali to give retinoyl β-glucuronide. The present invention is an improvement over the two-step procedure.