Acetyl chloride → Bis(1-methylethyl) B-phenylboronate

HRID 1722532Notes

Reaction equation

HRID 1722532 reaction equation
[C:1]1([Li])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH:8]([O:11][B:12](OC(C)C)[O:13][CH:14]([CH3:16])[CH3:15])([CH3:10])[CH3:9].C(Cl)(=O)C>>[C:1]1([B:12]([O:13][CH:14]([CH3:16])[CH3:15])[O:11][CH:8]([CH3:10])[CH3:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 3

HCID 6367Acetyl chlorideHCID 21531Triisopropyl borateHCID 178506676HCID 178506676, compound

Product 1

HCID 569210Bis(1-methylethyl) B-phenylboronate

Procedure

Following the procedure of Example 9, phenyllithium (17 mL, 30.6 mmol) and triisopropoxyborane (5.6 g, 30 mmol) were reacted, and the reaction quenched with acetyl chloride (2.1 mL, 30 mmol) to yield after distillation 5.2 g (25.2 mmol, 84%).

Workup

  1. customwere reacted
  2. customto yield
  3. distillationafter distillation 5.2 g (25.2 mmol, 84%)

Sources & evidence

ORD record
ord-f88a94fa88014212944c928838befb32
Source dataset
uspto-grants-1989_08
Patent number
US04855506

Reaction notes

Loading…