Benzyl Bromide → HCID 13318136, compound

HRID 1722579Notes

Reaction equation

HRID 1722579 reaction equation
[C:1]([NH:20][C:21]1[S:22][CH:23]=[C:24](/[C:26](=[N:32]/[OH:33])/[C:27]([O:29]CC)=[O:28])[N:25]=1)([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:34](Br)[C:35]1[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=1>>[C:1]([NH:20][C:21]1[S:22][CH:23]=[C:24](/[C:26](=[N:32]/[O:33][CH2:34][C:35]2[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=2)/[C:27]([OH:29])=[O:28])[N:25]=1)([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)([C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1)[C:8]1[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=1

Participants

3

Reactant 2

HCID 7498Benzyl BromideHCID 6410761(Z)-Ethyl 2-(hydroxyimino)-2-(2-(tritylamino)thiazol-4-yl)acetate

Product 1

HCID 13318136HCID 13318136, compound

Procedure

The starting material was prepared by reaction of ethyl 2-(2-tritylaminothiazol-4-yl)-2-((Z)hydroxyimino)acetate with benzyl bromide followed by hydrolysis of the ester to give 2-(2-tritylaminothiazol-4-yl)-2-((Z)-benzyloxyimino)acetic acid; n.m.r. in solvent C:-5.44(s, 2H); 6.69(s, 1H); 7.2-7.7(m, 20H).

Sources & evidence

ORD record
ord-25c3b1802517486c8d689af366965881
Source dataset
uspto-grants-1989_08
Patent number
US04855420

Reaction notes

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