Methyl iodide → HCID 20028883, compound

Participants

Reaction Steps

A mixture of 2-propyl-4-mercaptoquinazoline (3.3 g.) and sodium hydroxide (0.68 g.) in water (7 ml.) was stirred for 10 minutes at 25°. Methyl iodide (1.1 ml.) was added and stirring was continued for 1 hour. The precipitate was recrystallised from hexane to give 4-methylthio-2-propylquinazoline; n.m.r. in CDCl3 :-1.1(t, 3H); 1.95(m, 2H); 2.7(s, 3H); 3.0(t, 2H); 7.2-8.1(complex, 4H).

Provenance & Evidence