Hydrochloric Acid → HCID 14025169, compound

HRID 1722629Notes

Reaction equation

HRID 1722629 reaction equation
C[O:2][CH:3](OC)[C:4]1[NH:5][C:6]([CH3:31])=[C:7]([P:24]2(=[O:30])[O:29][CH2:28][CH2:27][CH2:26][O:25]2)[CH:8]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=2[C:20]([F:23])([F:22])[F:21])[C:9]=1[C:10]([O:12][CH3:13])=[O:11].Cl>CC(C)=O>[CH:3]([C:4]1[NH:5][C:6]([CH3:31])=[C:7]([P:24]2(=[O:30])[O:29][CH2:28][CH2:27][CH2:26][O:25]2)[CH:8]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=2[C:20]([F:23])([F:21])[F:22])[C:9]=1[C:10]([O:12][CH3:13])=[O:11])=[O:2]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 14025166HCID 14025166, compound

Product 1

HCID 14025169HCID 14025169, compoundYield 81.8%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

The dimethylacetal compound (1.43 g) obtained in Example 2 was dissolved in 6 ml of acetone, 1 ml of 6N hydrochloric acid was added thereto with ice cooling and stirring, the mixture was allowed to stand, stirred at ambient temperature for 1 hour, and purified by treating the same as that in Example 4 to give 1.06 g of oily product.

Workup

  1. stirringstirred at ambient temperature for 1 hour
  2. custompurified
  3. additionby treating the same as that in Example 4

Sources & evidence

ORD record
ord-74bb361a47724d64a6a255b3252cdd9e
Source dataset
uspto-grants-1989_08
Patent number
US04857515

Reaction notes

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