HCID 54369785, compound → HCID 53671948, compound

HRID 1722689Notes

Reaction equation

HRID 1722689 reaction equation
C([O:8][C:9](=[O:28])[C@H:10]([CH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)[CH2:11][C:12]([N:14]([CH2:16][CH:17]([OH:20])[CH2:18][OH:19])[CH3:15])=[O:13])C1C=CC=CC=1>CO.[Pd]>[CH3:15][N:14]([CH2:16][CH:17]([OH:20])[CH2:18][OH:19])[C:12]([CH2:11][C@@H:10]([CH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)[C:9]([OH:28])=[O:8])=[O:13]

Participants

4

Reactant 1

HCID 54369785HCID 54369785, compound

Product 1

HCID 53671948HCID 53671948, compoundYield 97%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

The resultant compound from Example 144 (200 mg, 0.523 mmol) and 10% Pd on carbon (200 mg) in methanol (10 ml) were stirred under a hydrogen atmosphere for 3 h. The reaction was filtered and evaporated to afford 148 mg (97%) of the desired product as an oil.

Workup

  1. filtrationThe reaction was filtered
  2. customevaporated

Sources & evidence

ORD record
ord-ce20a648af714842926b2cae260cfeb3
Source dataset
uspto-grants-1989_08
Patent number
US04857507

Reaction notes

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