1,1-Dimethylhydrazine → HCID 136126108, compound

Participants

Reaction Steps

A suspension of 3.46 g (10 mmol) of 6-[[(4-acetylphenyl)-2-propynylamino]methyl]-2-amino-4(3H)-quinazolinone (see Example 2j) and 6.01 g (100 mmol) of 1,1-dimethylhydrazine in 250 ml of methanol is heated under reflux for eighteen hours. The solution is concentrated and the residue recrystallized from methanol to give the product.

Provenance & Evidence