HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrahydrofuran → HCID 20027312, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | Diethylaminopropyl chloride, hydrochloride | HCID 145749 | — |
| Reactant | Magnesium | HCID 5462224 | — |
| Reactant | HCID 10796999 | HCID 10796999 | — |
| Product | HCID 20027312 | HCID 20027312 | — |
Reaction Steps
4-(2-Propynylamino)benzonitrile, 5 g (0.032 mol), in tetrahydrofuran is treated with an excess of the Grignard reagent which is prepared from fresh magnesium and 3-diethylaminopropyl chloride hydrochloride, according to the procedure of Sodet, Comptes Rendus, 254, pp. 3105-3107 (1962), to afford the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04857530 |
| Source dataset | uspto-grants-1989_08 |
| ORD ID | ord-8f3b034fb7e140618fa234dc619c5e3d |
| Source note | uspto-grants-1989_08 |