HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → 5-{5-[4-(2-Furanyl)phenoxy]pentyl}-3-methylisoxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 4-(2-Furyl)phenol | HCID 12247725 | — |
| Reactant | 5-(5-Bromopentyl)-3-methylisoxazole | HCID 13544046 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 5-{5-[4-(2-Furanyl)phenoxy]pentyl}-3-methylisoxazole | HCID 10086790 | — |
Reaction Steps
5-{5-[4-(2-Furanyl)phenoxy]pentyl}-3-methylisoxazole [II; R1 and R2 =H, Het=2-furanyl] was prepared from 3.6 g 4-(2-furanyl)phenol (m.p. 128-129° C., King and Walton, Synthesis 1976, p. 40), 5.4 g 5-(5-bromopentyl)-3-methylisoxazole and 1.5 g potassium hydroxide in acetonitrile according to the procedure of Example 1, part (c), and was obtained (4.2 g) as a light-tan solid, m.p. 86-88° C. when recrystallized from isopropyl acetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04857539 |
| Source dataset | uspto-grants-1989_08 |
| ORD ID | ord-84bddb7f130f4693a2769cefffc139e2 |
| Source note | uspto-grants-1989_08 |