HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanesulfonyl chloride → HCID 13603621, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | 2-[(2-Methoxyphenoxy)methyl]-1,3-thiazolidine | HCID 3025454 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Solvent | Sulfuric Acid | HCID 1118 | — |
| Product | HCID 13603621 | HCID 13603621 | 89.3% |
Reaction Steps
A solution of 2-(o-methoxyphenoxy)methyl-thiazolidine (1.83 g) in pyridine (6 ml) is treated with methane sulphonyl chloride (1.2 g) at room temperature. After 4 hours the mixture is diluted with 2N H2SO4, extracted with Et2O, to afford after the usual work-up 2.2 g of 3-methanesulphonyl-2-(o-methoxyphenoxy)methyl-thiazolidine m.p. 118°-120° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04857643 |
| Source dataset | uspto-grants-1989_08 |
| ORD ID | ord-b604238656cf439e8cade8f13ebf50be |
| Source note | uspto-grants-1989_08 |