Acetyl chloride → HCID 88483146, compound

HRID 1722877Notes

Reaction equation

HRID 1722877 reaction equation
[CH3:1][S+:2]([CH3:10])[C:3]1[CH:8]=[CH:7][C:6](O)=[CH:5][CH:4]=1.[CH3:11][O:12][S:13]([O-:16])(=[O:15])=[O:14].[C:17](Cl)(=[O:19])[CH3:18].C(N(CC)CC)C>C(#N)C>[CH3:11][O:12][S:13]([O-:16])(=[O:15])=[O:14].[CH3:1][S+:2]([CH3:10])[C:3]1[CH:8]=[CH:7][C:6]([CH2:18][C:17]([OH:19])=[O:12])=[CH:5][CH:4]=1

Participants

5

Reactant 3

HCID 6367Acetyl chlorideHCID 8471TriethylamineHCID 21915988(4-Hydroxyphenyl)(dimethyl)sulfanium methyl sulfate

Product 1

HCID 88483146HCID 88483146, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

In 30 ml of acetonitrile was dissolved 2.6 g of p-dimethylsulfoniophenol methylsulfate, and 0.8 ml of acetyl chloride and 1.4 ml of triethylamine were dropwise added thereto. The reaction mixture was filtered to remove the deposited triethylamine hydrochloride. The filtrate was concentrated under reduced pressure and the residue was crystallized by adding ether.

Workup

  1. additionwere dropwise added
  2. filtrationThe reaction mixture was filtered
  3. customto remove the deposited triethylamine hydrochloride
  4. concentrationThe filtrate was concentrated under reduced pressure
  5. customthe residue was crystallized
  6. additionby adding ether

Sources & evidence

ORD record
ord-496399c7f69441da82968cbb6b4b1f5a
Source dataset
uspto-grants-1989_08
Patent number
US04857656

Reaction notes

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